HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Thiazoleacetic acid, 2-amino-, ethyl ester → Ethyl (2-{[(5-bromo-2-methoxyphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Thiazoleacetic acid, 2-amino-, ethyl ester | HCID 104454 | — |
| Reactant | 5-Bromo-2-methoxybenzene-1-sulfonyl chloride | HCID 520020 | — |
| Product | Ethyl (2-{[(5-bromo-2-methoxyphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate | HCID 3779070 | — |
Reaction Steps
The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 5-bromo-2-methoxybenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (14.4 mg) with purity >90%. LCMS (pos) m/z 437.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618961B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-236f71fb441a4bc1ad8aae5aabcdfc3c |
| Source note | uspto-grants-2009_11 |