2-Mesitylenesulfonyl chloride → HCID 3752975, compound

HRID 1435647Notes

Reaction equation

HRID 1435647 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1.[C:13]1([CH3:25])[CH:18]=[C:17]([CH3:19])[CH:16]=[C:15]([CH3:20])[C:14]=1[S:21](Cl)(=[O:23])=[O:22]>>[C:13]1([CH3:25])[CH:18]=[C:17]([CH3:19])[CH:16]=[C:15]([CH3:20])[C:14]=1[S:21]([NH:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1)(=[O:22])=[O:23]

Participants

3

Reactant 2

HCID 130462-Mesitylenesulfonyl chlorideHCID 1044544-Thiazoleacetic acid, 2-amino-, ethyl ester

Product 1

HCID 3752975HCID 3752975, compound

Procedure

The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 2-mesitylenesulfonyl chloride as described in the synthetic METHOD B to give a white-yellow solid (7.5 mg) with purity >90%. LCMS (pos) m/z 369.0.

Sources & evidence

ORD record
ord-2bb1e6546dd94ea882fe9b4ce451ea65
Source dataset
uspto-grants-2009_11
Patent number
US07618961B2

Reaction notes

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