1-Naphthalenesulfonyl chloride → HCID 10177549, compound

Participants

Reaction Steps

The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 1-naphthylsulfonyl chloride according to METHOD A, giving a crude product that was purified by flash column chromatography on silica gel eluting with 2% methanol in DCM. This gave the pure title compound (3.93 g, 89%). MS (Ionspray, [M+H]+) m/z 376; Anal. Calcd. (found) for C17H16N2O4S2: C, 54.2 (54.02)%; H, 4.3 (3.9)%; N, 7.4 (7.1)%.

Provenance & Evidence