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HRID 1435674作成日:2026年10月25日

4-Thiazoleacetic acid, 2-amino-, ethyl ester → Ethyl (2-{[(2,4,6-trifluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate

https://huagongshe.com/reaction/1435674

反応式

関与物質

役割名称HCID仕込み量
反応物4-Thiazoleacetic acid, 2-amino-, ethyl esterHCID 104454—
反応物2,4,6-Trifluorobenzenesulfonyl chlorideHCID 2776983—
生成物Ethyl (2-{[(2,4,6-trifluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetateHCID 10110297—

反応手順

The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 2,4,6-trifluorobenzenesulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (1.0 mg) with purity >90%. MS (pos) m/z 381.4.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07618961B2
出典データセットuspto-grants-2009_11
ORD IDord-6a3ca502d9984c77b9680e1a8aadb839
出典メモuspto-grants-2009_11