HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Thiazoleacetic acid, 2-amino-, ethyl ester → Ethyl (2-{[(2-chloro-4-fluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Thiazoleacetic acid, 2-amino-, ethyl ester | HCID 104454 | — |
| Reactant | 2-Chloro-4-fluorobenzene-1-sulfonyl chloride | HCID 522846 | — |
| Product | Ethyl (2-{[(2-chloro-4-fluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate | HCID 10156542 | — |
Reaction Steps
The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 2-chloro-4-fluorobenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (13.9 mg) with purity >90%. MS (pos) m/z 379.2, 381.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618961B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-99af3c7ba81c4d0da5f0a752b016021a |
| Source note | uspto-grants-2009_11 |