4-Thiazoleacetic acid, 2-amino-, ethyl ester → HCID 10223773, compound

HRID 1435680Notes

Reaction equation

HRID 1435680 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1.[CH:13]1[CH:18]=[CH:17][C:16]([O:19][C:20]2[CH:25]=[CH:24][C:23]([S:26](Cl)(=[O:28])=[O:27])=[CH:22][CH:21]=2)=[CH:15][CH:14]=1>>[O:19]([C:20]1[CH:25]=[CH:24][C:23]([S:26]([NH:1][C:2]2[S:3][CH:4]=[C:5]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=2)(=[O:28])=[O:27])=[CH:22][CH:21]=1)[C:16]1[CH:15]=[CH:14][CH:13]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 1044544-Thiazoleacetic acid, 2-amino-, ethyl esterHCID 27947564-Phenoxybenzene-1-sulfonyl chloride

Product 1

HCID 10223773HCID 10223773, compound

Procedure

The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and [(4-phenoxy)benzene]sulfonyl chloride as described in the synthetic METHOD B to give a white solid (33.5 mg) with purity >90%. MS (pos) m/z 419.3.

Sources & evidence

ORD record
ord-d5118549d5a348f9917128c5ec4bba6d
Source dataset
uspto-grants-2009_11
Patent number
US07618961B2

Reaction notes

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