HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-2-methylbenzenesulfonyl chloride → Ethyl (2-{[(3-chloro-2-methylphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)(oxo)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-2-methylbenzenesulfonyl chloride | HCID 522734 | — |
| Reactant | Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate | HCID 4356513 | — |
| Product | Ethyl (2-{[(3-chloro-2-methylphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)(oxo)acetate | HCID 10293667 | — |
Reaction Steps
The title compound was prepared from ethyl (2-amino-4-thiazolyl)glyoxylate and 3-chloro-2-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (32.5 mg) with purity >90%. LCMS (pos) m/z 389.0.B
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618961B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-2946cbcffe504c3290773c9e51c37607 |
| Source note | uspto-grants-2009_11 |