HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzenesulfonyl chloride → Methyl (2-{[(4-chlorophenyl)sulfonyl]amino}-5-methyl-1,3-thiazol-4-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzenesulfonyl chloride | HCID 7398 | — |
| Reactant | Methyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate | HCID 2763571 | — |
| Product | Methyl (2-{[(4-chlorophenyl)sulfonyl]amino}-5-methyl-1,3-thiazol-4-yl)acetate | HCID 86594952 | — |
Reaction Steps
The title compound was prepared from methyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate and 4-chlorobenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (29.2 mg) with purity >90%. LCMS (pos) m/z 361.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618961B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-543906b7a84443518e12b9ef623cce31 |
| Source note | uspto-grants-2009_11 |