HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-camphorsulfonic acid → (s)-5-Bromo-2,3-dihydro-1h-inden-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-camphorsulfonic acid | HCID 131278 | — |
| Reactant | 5-bromo-2,3-dihydro-1H-inden-2-amine | HCID 11298795 | — |
| Product | (s)-5-Bromo-2,3-dihydro-1h-inden-2-amine | HCID 46899973 | — |
| Product | (s)-5-Bromo-2-aminoindan (1r)-(-)-10-camphorsulfonate salt | HCID 86633675 | — |
Reaction Steps
The title compound was prepared using a similar method to that described in Prashad et al, Adv. Synth. Catal. 2001, 343, No. 5, pp 461-472: ie by resolution of the free base form of racemic 5-bromo-2-aminoindan using (1R)-(−)-10-camphorsulphonic acid to obtain (S)-5-bromo-2-aminoindan (1R)-(−)-10-camphorsulfonate salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618969B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-38783aae35484c7d9f9e3cbaa105d561 |
| Source note | uspto-grants-2009_11 |