5-Bromo-2,3-dihydro-1H-inden-2-amine--hydrogen bromide (1/1) → N-(5-bromo-2,3-dihydro-1H-inden-2-yl)-2-propanesulfonamide

HRID 1435718Notes

Reaction equation

HRID 1435718 reaction equation
Br.[Br:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[CH2:8][CH:7]([NH2:12])[CH2:6]2.C1C2C(=CC=CC=2)CC1N[S:23]([CH:26]([CH3:28])[CH3:27])(=[O:25])=[O:24]>>[Br:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[CH2:8][CH:7]([NH:12][S:23]([CH:26]([CH3:28])[CH3:27])(=[O:25])=[O:24])[CH2:6]2

Participants

3

Reactant 2

HCID 121920575-Bromo-2,3-dihydro-1H-inden-2-amine--hydrogen bromide (1/1)HCID 46899808N-(2,3-dihydro-1H-inden-2-yl)-2-propanesulfonamide

Product 1

HCID 66734053N-(5-bromo-2,3-dihydro-1H-inden-2-yl)-2-propanesulfonamide

Procedure

The title compound was prepared from 5-bromo-2-aminoindane hydrobromide (Prashad et al, Adv. Synth. Catal. 2001, 343, No. 5, pp 461-472) by a similar process to the preparation of Intermediate 1.

Sources & evidence

ORD record
ord-1b8205595aea48d2b289ebae425cda1b
Source dataset
uspto-grants-2009_11
Patent number
US07618969B2

Reaction notes

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