HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Hydroxymethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one → 3-Oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Hydroxymethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one | HCID 21873700 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carbaldehyde | HCID 10943348 | 72.2% |
Reaction Steps
A stirred solution of 6-hydroxymethyl-4H-benzo[1,4]thiazin-3-one (3.5 g) in chloroform (150 mL) and tetrahydrofuran (300 mL) was treated with manganese dioxide (7.8 g) for 18 hours and was filtered and evaporated to give a white solid (2.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618959B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-7dedef2d37544c4c85ef2cbb46b6c020 |
| Source note | uspto-grants-2009_11 |