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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435879Generated: October 26, 2026

Hydrochloric Acid → HCID 68441439, compound

https://huagongshe.com/reaction/1435879

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,1-Dimethylethyl (2-(5-[6-(methyloxy)-1,5-naphthyridin-4-yl]-2-pyridinyl}ethyl)carbamateHCID 57938630—
SolventTetrahydrofuranHCID 8028—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 68441439HCID 68441439100%

Reaction Steps

To a stirred solution of 1,1-dimethylethyl (2-(5-[6-(methyloxy)-1,5-naphthyridin-4-yl]-2-pyridinyl}ethyl)carbamate (4.0 mmole) in dry THF (20 mL) at RT was added 4 M HCl in dioxane (10 mL). After 4 h, the reaction suspension was concentrated in vacuo and dried under high vacuum to give the title compound (100%.) as an off-white solid: LC-MS (ES) m/e 281 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618959B2
Source datasetuspto-grants-2009_11
ORD IDord-6e8dd28c06b840a2a8c4cda44c486ace
Source noteuspto-grants-2009_11