(4-Methoxy-2-methylphenyl)boronic acid → HCID 11544358, compound

Participants

Reaction Steps

Following the procedures described in Example 12, except that 4-methoxy-2-methylphenylboronic acid was used instead of phenylboronic acid, (±)-cis-tert-butyl 8-bromo-6-methoxy-3,3a,4,5-tetrahydro-1H-pyrrolo[3,4-c]quinoline-2(9bH)-carboxylate from Example 11, Part A was converted into the title compound of Example 14. 1H NMR (CDCl3): δ 7.14 (d, 1H, J=8.1 Hz), 6.83-6.73 (m, 2H), 6.62 (s, 1H), 6.61 (s, 1H), 4.49 (broad s, 1H), 3.85 (s, 3H), 3.84 (s, 3H), 3.78-3.70 (m, 1H), 3.62-3.05 (overlapping m, 6H), 2.83-2.75 (m, 1H), 2.28 (s, 3H). LRMS (ES)+: 325.4 (M+H)+.

Provenance & Evidence