(2,4-Dichlorophenyl)boronic acid → HCID 11581073, compound

Participants

Reaction Steps

Following the procedures described in Example 12, except that 2,4-dichlorophenylboronic acid was used instead of phenylboronic acid, (±)-cis-tert-butyl 8-bromo-6-methoxy-3,3a,4,5-tetrahydro-1H-pyrrolo[3,4-c]quinoline-2(9bH)-carboxylate from Example 11, Part A was converted into the title compound of Example 15. 1H NMR (CDCl3): δ 7.48 (s, 1H), 7.34-7.25 (m, 2H), 6.76 (s, 1H), 6.74 (s, 1H), 4.55 (broad s, 1H), 3.87 (s, 3H), 3.65-3.57 (m, 1H), 3.50-3.25 (overlapping m, 4H), 3.13-2.97 (m, 2H), 2.75-2.65 (m, 1H). LRMS (ES)+: 349.3/351.3 (M+H)+.

Provenance & Evidence