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(S)-1-Benzyl-3-mesyloxypyrrolidine → (r)-6-(1-Benzylpyrrolidin-3-yloxy)-isoquinolin-1-ylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (S)-1-Benzyl-3-mesyloxypyrrolidine | HCID 10934081 | — |
| 反応物 | 1-Aminoisoquinolin-6-ol | HCID 135753991 | — |
| 生成物 | (r)-6-(1-Benzylpyrrolidin-3-yloxy)-isoquinolin-1-ylamine | HCID 68874478 | — |
反応手順
This compound was prepared from (S)-methanesulfonic acid 1-benzylpyrrolidin-3-yl ester and 1-amino-6-hydroxyisoquinoline by the procedure described in Example 1 to give the (R) 6-(1-benzylpyrrolidin-3-yloxy)-isoquinolin-1-ylamine product, El-MS: m/z=320.3 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07618985B2 |
| 出典データセット | uspto-grants-2009_11 |
| ORD ID | ord-460cd1046de4481ab224757e8ef6c692 |
| 出典メモ | uspto-grants-2009_11 |