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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1436038Generated: October 31, 2026

(r/s)-3-(Tert-butoxycarbonylamino)-1-(4-bromo-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/1436038

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(r/s)-3-(Tert-butoxycarbonylamino)-1-(4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 67242856—
ReactantHCID 67243204HCID 67243204—
ProductHydrochloric AcidHCID 313—
ProductHCID 178511749HCID 178511749—

Reaction Steps

Intermediate 16b is used in the method of Example 6, Step A instead of Intermediate 1, then the resultant is used in the method of Step B in a similar manner, and then the title compound is obtained as hydrochloride according to the method described in Example 7.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618984B2
Source datasetuspto-grants-2009_11
ORD IDord-74a211b68fd045c4bb28698ea935bfbc
Source noteuspto-grants-2009_11