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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1436052Generated: October 27, 2026

(R)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/1436052

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 86627809—
Reactant(r/s)-3-(Tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 87322862—
ProductHydrochloric AcidHCID 313—
Product(R)-3-Amino-1-(1-amino-4-chloro-5-isoquinolinesulfonyl)pyrrolidineHCID 67246845—

Reaction Steps

Intermediate 26b is used in the method of Example 39 instead of Intermediate 26 to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618984B2
Source datasetuspto-grants-2009_11
ORD IDord-feaaccb29e9d4b999888fb4269401837
Source noteuspto-grants-2009_11