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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1436058Generated: November 3, 2026

(S)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]-1-(1-chloro-4-bromo-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/1436058

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]-1-(1-chloro-4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 86627805—
Reactant(r/s)-3-(Tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 87322862—
ProductHydrochloric AcidHCID 313—
ProductHCID 67243568HCID 67243568—

Reaction Steps

Intermediate 24a was used in the method of Example 39 instead of Intermediate 26 to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618984B2
Source datasetuspto-grants-2009_11
ORD IDord-24bf90621c7546c796ee8b36ff6e2702
Source noteuspto-grants-2009_11