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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1436059Generated: October 31, 2026

(R)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]-1-(1-chloro-4-bromo-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/1436059

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]-1-(1-chloro-4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 86627806—
Reactant(r/s)-3-(Tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 87322862—
ProductHydrochloric AcidHCID 313—
ProductHCID 67242679HCID 67242679—

Reaction Steps

Intermediate 24b is used in the method of Example 39 instead of Intermediate 26 to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618984B2
Source datasetuspto-grants-2009_11
ORD IDord-9dd96ca547724e7f9959ba943fe2db92
Source noteuspto-grants-2009_11