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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1436229Generated: November 1, 2026

2-Morpholinoethylamine → HCID 11223120, compound

https://huagongshe.com/reaction/1436229

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MorpholinoethylamineHCID 408285—
Reactant2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amineHCID 11738112—
ProductHCID 11223120HCID 11223120—

Reaction Steps

The title compound was prepared from (2-chloro-quinazolin-4-yl)-(4-methoxy-phenyl)-methyl-amine (10 mg, 0.033 mmol) and 2-morpholin-4-yl-ethylamine (30 μL) by a procedure similar to example 10 and was isolated as white powder (10 mg, 100%). 1H NMR (CDCl3): 7.42 (dd, J=8.7 and 1.2 Hz, 1H), 7.36 (ddd, J=8.1, 6.6 and 1.5 Hz, 1H), 7.10-7.09 (m, 2H), 6.92-6.86 (m, 3H), 6.67 (ddd, J=8.1, 6.6 and 1.4 Hz, 1H), 3.82 (s, 3H), 3.75-3.62 (m, 6H), 3.52 (s, 3H), 2.55-2.44 (m, 6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618975B2
Source datasetuspto-grants-2009_11
ORD IDord-492e97260e5f480588f26ac231a35f13
Source noteuspto-grants-2009_11