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Benzenamine, N,4-dimethyl- → (2-Chloro-6,7-dimethoxyquinazolin-4-yl)-(4-methyl-phenyl)-methyl-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzenamine, N,4-dimethyl- | HCID 12165 | — |
| 反応物 | 2,4-Dichloro-6,7-dimethoxyquinazoline | HCID 520327 | — |
| 生成物 | (2-Chloro-6,7-dimethoxyquinazolin-4-yl)-(4-methyl-phenyl)-methyl-amine | HCID 57938798 | — |
反応手順
The title compound was prepared from 2,4-dichloro-6,7-dimetoxyquinazoline (100 mg, 0.386 mmol) and N-methyl-p-tolylamine (49 mg, 0.386 mmol) by a procedure similar to example 1b and was isolated as white powder (8 mg, 8%). 1H NMR (CDCl3): 7.27 (d, J=8.4 Hz, 2H), 7.15 (d, J=8.4 Hz, 2H), 7.08 (s, 1H), 6.26 (s, 1H), 3.92 (s, 3H), 3.61 (s, 3H), 3.28 (s, 3H), 2.37 (s, 3H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07618975B2 |
| 出典データセット | uspto-grants-2009_11 |
| ORD ID | ord-9c91aa34a04843efa4811d064004953e |
| 出典メモ | uspto-grants-2009_11 |