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HRID 1436234作成日:2026年10月25日

Benzenamine, N,4-dimethyl- → (2-Chloro-6,7-dimethoxyquinazolin-4-yl)-(4-methyl-phenyl)-methyl-amine

https://huagongshe.com/reaction/1436234

反応式

関与物質

役割名称HCID仕込み量
反応物Benzenamine, N,4-dimethyl-HCID 12165—
反応物2,4-Dichloro-6,7-dimethoxyquinazolineHCID 520327—
生成物(2-Chloro-6,7-dimethoxyquinazolin-4-yl)-(4-methyl-phenyl)-methyl-amineHCID 57938798—

反応手順

The title compound was prepared from 2,4-dichloro-6,7-dimetoxyquinazoline (100 mg, 0.386 mmol) and N-methyl-p-tolylamine (49 mg, 0.386 mmol) by a procedure similar to example 1b and was isolated as white powder (8 mg, 8%). 1H NMR (CDCl3): 7.27 (d, J=8.4 Hz, 2H), 7.15 (d, J=8.4 Hz, 2H), 7.08 (s, 1H), 6.26 (s, 1H), 3.92 (s, 3H), 3.61 (s, 3H), 3.28 (s, 3H), 2.37 (s, 3H).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07618975B2
出典データセットuspto-grants-2009_11
ORD IDord-9c91aa34a04843efa4811d064004953e
出典メモuspto-grants-2009_11