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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1436244Generated: October 29, 2026

N-Methyl-4-anisidine → (4-Methoxy-phenyl)-methyl-quinazolin-4-yl-amine

https://huagongshe.com/reaction/1436244

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant4-ChloroquinazolineHCID 78864—
Product(4-Methoxy-phenyl)-methyl-quinazolin-4-yl-amineHCID 11254113—

Reaction Steps

The title compound was prepared from 4-chloroquinazoline and 4-methoxy-N-methylaniline by a procedure similar to example 28 (79% yield). 1H NMR (CDCl3): 8.81 (s, 1H), 7.81 (d, J=8.1 Hz, 1H), 7.57 (ddd, J=8.1, 5.4 and 2.7 Hz, 1H), 7.09-7.14 (m, 2H), 7.03-7.06 (m, 2H), 6.9-6.93 (m, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618975B2
Source datasetuspto-grants-2009_11
ORD IDord-5276d931959049589653d6bd271cf052
Source noteuspto-grants-2009_11