HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → N-(4-Methoxyphenyl)-N-methyl-2-phenylquinazolin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | N-(4-methoxyphenyl)-2-phenylquinazolin-4-amine | HCID 719284 | — |
| Product | N-(4-Methoxyphenyl)-N-methyl-2-phenylquinazolin-4-amine | HCID 57938808 | — |
Reaction Steps
The title compound was prepared from (4-methoxy-phenyl)-(2-phenyl-quinazolin-4-yl)-amine (51 mg, 0.16 mmol) and methyl iodide (0.07 ml, 1.09 mmol) by a procedure similar to Example 36. 1H NMR (CDCl3): 8.64-8.61 (m, 2H), 7.90 (d, J=8.4 Hz, 1H), 7.59-7.48 (m, 4H), 7.18-7.14 (m, 2H), 7.08-6.98 (m, 2H), 6.94-6.91 (m, 2H), 3.85 (s, 3H), 3.73 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618975B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-8e2de9e7e7594382a09814e21b56e0e7 |
| Source note | uspto-grants-2009_11 |