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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1436339Generated: November 1, 2026

2,2,3,3-Tetrafluoro-1-propanol → HCID 86621591, compound

https://huagongshe.com/reaction/1436339

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2,3,3-Tetrafluoro-1-propanolHCID 6441—
Reactant6-Chloro-3-pyridinecarbonitrileHCID 5152094—
Reactant3-Pyridinemethanamine, alpha-methyl-6-(2,2,2-trifluoroethoxy)-HCID 58629100—
ProductHCID 86621591HCID 86621591—

Reaction Steps

The title compound was synthesised according to the 2-step procedure described for the synthesis of 1-[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]ethanamine starting from 6-chloronicotinonitrile and 2,2,3,3-tetrafluoropropan-1-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618993B2
Source datasetuspto-grants-2009_11
ORD IDord-cf220fe356ae435c9368748f3c3cecf8
Source noteuspto-grants-2009_11