HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 23624253, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | HCID 23624258 | HCID 23624258 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 23624253 | HCID 23624253 | 50% |
Reaction Steps
5-(1H-indol-5-yl)-2,3,4,5-tetrahydro-1H-benzo[c]azepine was subjected to reductive amination using formaldehyde and sodium triacetoxyborohydride in 1,2-dichloroethane to give 5-(1H-indol-5-yl)-2-methyl-2,3,4,5-tetrahydro-1H-benzo[c]azepine as a white powder in 50% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07622462B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-44d21bdfcd5e4604817933cdc3fc9f77 |
| Source note | uspto-grants-2009_11 |