N,N-Diethylethylenediamine → HCID 178464052, compound

HRID 1437006Notes

Reaction equation

HRID 1437006 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[C:8](=O)[NH:7][C:6]=2[CH:17]=1.[CH2:18]([N:20]([CH2:24][CH3:25])[CH2:21][CH2:22][NH2:23])[CH3:19]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[C:8]([NH:23][CH2:22][CH2:21][N:20]([CH2:24][CH3:25])[CH2:18][CH3:19])=[N:7][C:6]=2[CH:17]=1

Participants

3

Reactant 2

HCID 60993N,N-DiethylethylenediamineHCID 36531168-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one

Product 1

HCID 178464052HCID 178464052, compoundYield 11.4%

Procedure

8-Chloro-5,10-dihydro-dibenzo[b,e][1,4]diazepine-11-one (25 mg, 0.1 mmol) and N,N-diethylethylenediamine (58 mg, 0.5 mmol) were reacted according to GP4 to give 3.9 mg of the title compound (160FE16E). MS (ESI) 343 (MH+). Purity for MH+ (UV/MS) 99/94.

Sources & evidence

ORD record
ord-be2f9496fdbb496e9a577975ac49fb8a
Source dataset
uspto-grants-2009_11
Patent number
US07622461B2

Reaction notes

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