Methyl 2-(2-chloroethoxy)benzoate → HCID 68894785, compound

HRID 1437161Notes

Reaction equation

HRID 1437161 reaction equation
[O:1]1[CH:5]=[CH:4][C:3]([CH2:6][N:7]2[C:11]3=[N:12][CH:13]=[CH:14][CH:15]=[C:10]3[C:9]([CH:16]3[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]3)=[CH:8]2)=[CH:2]1.[CH3:22][O:23][C:24](=[O:35])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[O:31][CH2:32][CH2:33]Cl>>[CH3:22][O:23][C:24](=[O:35])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[O:31][CH2:32][CH2:33][N:19]1[CH2:18][CH2:17][CH:16]([C:9]2[C:10]3[C:11](=[N:12][CH:13]=[CH:14][CH:15]=3)[N:7]([CH2:6][C:3]3[CH:4]=[CH:5][O:1][CH:2]=3)[CH:8]=2)[CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 9837283Methyl 2-(2-chloroethoxy)benzoateHCID 68896318HCID 68896318, compound

Product 1

HCID 68894785HCID 68894785, compound

Procedure

This compound was prepared following the procedure described in example 1, part H, starting with 0.28 g (1 mmol) of 1-furan-3-ylmethyl-3-piperidin-4-yl-1H-pyrrolo[2,3-b]pyridine and 0.26 g (1.2 mmol) of 2-(2-chloroethoxy)-benzoic acid methyl ester. After standard work-up and purification, 0.16 g (35% of yield) of the expected product were obtained.

Workup

  1. customThis compound was prepared
  2. customAfter standard work-up and purification, 0.16 g (35% of yield) of the expected product
  3. customwere obtained

Sources & evidence

ORD record
ord-26aa4a48a448422b92e0f04b6ddddceb
Source dataset
uspto-grants-2009_11
Patent number
US07622480B2

Reaction notes

Loading…