5-Hydrazinyl-2-methoxypyridine → HCID 57940639, compound

HRID 1437242Notes

Reaction equation

HRID 1437242 reaction equation
[CH2:1]([O:3][C:4](=[O:18])[C:5](=O)[CH2:6][C:7]([C:9]1[CH:14]=[C:13]([S:15][CH3:16])[CH:12]=[CH:11][N:10]=1)=O)[CH3:2].[NH:19]([C:21]1[CH:22]=[CH:23][C:24]([O:27][CH3:28])=[N:25][CH:26]=1)[NH2:20]>>[CH2:1]([O:3][C:4]([C:5]1[CH:6]=[C:7]([C:9]2[CH:14]=[C:13]([S:15][CH3:16])[CH:12]=[CH:11][N:10]=2)[N:19]([C:21]2[CH:26]=[N:25][C:24]([O:27][CH3:28])=[CH:23][CH:22]=2)[N:20]=1)=[O:18])[CH3:2]

Participants

3

Reactant 2

HCID 222178535-Hydrazinyl-2-methoxypyridineHCID 57940661HCID 57940661, compound

Product 1

HCID 57940639HCID 57940639, compoundYield 16.3%

Procedure

The general procedure of Referential Example 3-2) was repeated through use of 4-(4-methylthio-2-pyridyl)-2,4-dioxobutanoic acid ethyl ester (1.62 g) and the 5-hydrazino-2-methoxypyridine (0.843 g) prepared in Referential Example 2, to thereby give the title compound as a solid (0.366 g, 16%).

Sources & evidence

ORD record
ord-55b7ed21a0e4450ea90f3aa071d8c857
Source dataset
uspto-grants-2009_11
Patent number
US07622471B2

Reaction notes

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