HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → N-methylpiperidine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | N-benzyloxypiperidine-2-carboxylic acid | HCID 23090179 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-methylpiperidine-2-carboxamide | HCID 9989361 | — |
Reaction Steps
The general procedure of Referential Example 131 was repeated through use of N-benzyloxypiperidine-2-carboxylic acid (2.0 g) and 1.0 M methylamine in tetrahydrofuran (4 mL), to thereby give the title compound as an oily product (970 mg, quantitative amount).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07622471B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-e7d34bec75684832a71b0a225f0e3b6c |
| Source note | uspto-grants-2009_11 |