HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Hydroxymethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one → 3-Oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Hydroxymethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one | HCID 21873700 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carbaldehyde | HCID 10943348 | 72.2% |
Reaction Steps
A stirred solution of the alcohol (b) (3.5 g) in chloroform (150 ml) and tetrahydrofuran (300 ml) was treated with manganese dioxide (7.8 g) for 18 hours and was filtered and evaporated to give a white solid (2.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07622481B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-2aaf477b8352419d9d7dc710e955a5bb |
| Source note | uspto-grants-2009_11 |