Potassium Carbonate → HCID 68702155, compound

Participants

Reaction Steps

4-Nitrobenzoic acid (1S,2R,5R)-2-tert-butoxycarbonylamino-5-carbamoyl-cyclohexyl ester (i) (3.62 g, 8.9 mmol) in dry MeOH (250 mL) was treated with potassium carbonate (1.84 g, 13.3 mmol). After 2 hours at room temperature, the mixture was concentrated and the residue purified by flash column chromatography (silica gel, DCM/MeOH, 5-15%) to give a white solid (1.62 g, 6.3 mmol, 71%).

Provenance & Evidence