HCID 68703264, compound → HCID 68701552, compound

HRID 1437372Notes

Reaction equation

HRID 1437372 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][Si:11]([CH:18]([CH3:20])[CH3:19])([CH:15]([CH3:17])[CH3:16])[CH:12]([CH3:14])[CH3:13])[C:5]=1[NH2:21])([O-])=O>C(O)C.[Pd]>[CH:18]([Si:11]([CH:12]([CH3:14])[CH3:13])([CH:15]([CH3:17])[CH3:16])[O:10][C:6]1[CH:7]=[CH:8][CH:9]=[C:4]([NH2:1])[C:5]=1[NH2:21])([CH3:20])[CH3:19]

Participants

4

Reactant 1

HCID 68703264HCID 68703264, compound

Product 1

HCID 68701552HCID 68701552, compoundYield 98.2%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of (a) (91 g) in ethanol (500 ml) was hydrogenated over 10% palladium on charcoal (8.5 g) for 3 days then filtered and evaporated to give an oil (80.7 g).

Workup

  1. filtrationthen filtered
  2. customevaporated

Sources & evidence

ORD record
ord-1696493fe3444be8ac135d2362a37f15
Source dataset
uspto-grants-2009_11
Patent number
US07622481B2

Reaction notes

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