HCID 68703262, compound → HCID 86607260, compound

Participants

Reaction Steps

Carbamate (h) (110 mg, 0.27 mmol) was dissolved in dichloromethane/triluoroacetic acid (2 ml/2 ml). After 1 hour the mixture was evaporated to dryness and the residue triturated with ether. The residue was then redissolved in 10% methanol in dichloromethane (20 ml) and treated with macroporous triethylammonium methylpolystyrene carbonate resin (2.8 mmol/g; 2.7 g, Argonaut Technologies). After 1 hour the mixture was filtered and the resin washed several times alternately with 10% methanol in dichloromethane then methanol. The combined filtrate and washings were evaporated affording a white solid (80 mg, 95%).

Provenance & Evidence