HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(5-acetyl-2-methyl-indan-2-yl)-benzamide → N-(5-Ethyl-2-methyl-indan-2-yl)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(5-acetyl-2-methyl-indan-2-yl)-benzamide | HCID 22499217 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-(5-Ethyl-2-methyl-indan-2-yl)-benzamide | HCID 22499186 | — |
Reaction Steps
A solution of N-(5-acetyl-2-methyl-indan-2-yl)-benzamide (3.4 g) in ethanol (200 ml) and conc. HCl (2 ml) is stirred under hydrogen in the presence of 10% Pd/C at room temperature for 48 hours. The mixture is filtered through celite and the filtrate is concentrated in vacuo to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07622483B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-a4fc097225924cd985b6e95e9d0cb10b |
| Source note | uspto-grants-2009_11 |