HCID 23025756, compound → HCID 23025814, compound

Participants

Reaction Steps

Under a hydrogen stream, a suspension of 3-nitro-6-phenoxy-2-pyridine amine (Compound of Reference Example 114) (0.1 g), palladium-carbon (10 mg) and methanol (2 ml) were stirred at room temperature for 10 hours. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure. The residue was subjected to silica gel chromatography and the fraction eluted with ethyl acetate-hexane (1:1, v/v) was concentrated under reduced pressure to obtain 6-phenoxy-2,3-pyridine diamine (0.06 g, 59%).

Provenance & Evidence