Dimethylformamide → HCID 68898032, compound

Participants

Reaction Steps

To a solution consisting of 2-[[2-(3-methoxyphenyl)-6-phenyl-1H-imidazo[4,5-b]pyridin-1-yl]methyl]phenol (Compound of Example 157) (41 mg), bromoethyl acetate (18 mg), N,N-dimethyl formamide (1 ml) was added potassium carbonate (19 mg), and the mixture was stirred at room temperature for 2 hours. The reaction mixture was poured into water and extracted with ethyl acetate. The organic layer was washed with water and dried over MgSO4. The solvent was distilled off under reduced pressure, and the resulting crystals were collected by filtration to obtain [2-[[2-(3-methoxyphenyl)-6-phenyl-1H-imidazo[4,5-b]pyridin-1-yl]methyl]phenoxy]ethyl acetate (37 mg, 74%).

Provenance & Evidence