Cyclohexanone → HCID 69011507, compound

HRID 1437498Notes

Reaction equation

HRID 1437498 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:10])[CH3:9].[C:11]1(=O)[CH2:15][CH2:14][CH2:13][CH2:12]1.[C:17]1(=[O:23])CCCC[CH2:18]1>>[CH2:17]([O:23][C:6]1[CH:7]=[C:2]2[C:3]([C:8](=[O:10])[CH2:9][C:11]3([O:1]2)[CH2:15][CH2:14][CH2:13][CH2:12]3)=[CH:4][CH:5]=1)[CH3:18]

Participants

4

Reactant 3

HCID 7967CyclohexanoneHCID 83752'-HydroxyacetophenoneHCID 8452Cyclopentanone

Product 1

HCID 69011507HCID 69011507, compound

Procedure

The title compound was prepared using the procedure as described in Example 1A, substituting 4′-ethoxy-2′-hydroxyacetophenone (Aldrich, CAS# 37470-42-1) for 2′-hydroxyacetophenone and cyclopentanone for cyclohexanone. 1H NMR (300 MHz, DMSO-d6) δ ppm 7.65 (d, J=8.6 Hz, 1H), 6.57 (dd; J=8.4, 2.3 Hz; 1H), 6.45 (d, J=2.4 Hz, 1H), 4.08 (q, J=7.1 Hz, 2H), 2.79 (s, 2H), 1.94 (m, 2H), 1.60-1.80 (m, 6H), 1.32 (t, J=7.0 Hz, 3H). MS (DCI+) m/z 247 (M+H), 264 (M+NH4).

Sources & evidence

ORD record
ord-170d4403b3604aafbfb62da53b85dbff
Source dataset
uspto-grants-2009_11
Patent number
US07622493B2

Reaction notes

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