HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanone → HCID 69010660, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | 2'-Hydroxyacetophenone | HCID 8375 | — |
| Reactant | 4'-Fluoro-2'-hydroxyacetophenone | HCID 2737326 | — |
| Reactant | 1''-Methyl-3,4-dihydrospiro[chromene-2,4''-piperidin]-4-amine hydrochloride | HCID 4961682 | — |
| Product | HCID 69010660 | HCID 69010660 | — |
Reaction Steps
The title compound was prepared using the procedure as described in Example 1A, substituting tetrahydro-4H-pyran-4-one for cyclohexanone and 4′-fluoro-2′hydroxyacetophenone for 2′-hydroxyacetophenone. 1 NMR (300 MHz, DMSO-d6) δ ppm 7.80 (dd, J=8.81, 6.78 Hz, 1H), 6.87-7.01 (m, 2H), 3.62-3.74 (m, 4H), 2.86 (s, 2H), 1.73-1.86 (m, 4H). MS (DCI+) m/z 237 (M+H), 254 (M+NH4).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07622493B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-faa4bd8417fb4086aae26b5a38a745e5 |
| Source note | uspto-grants-2009_11 |