Sodium cyanoborohydride → HCID 13558941, compound

Participants

Reaction Steps

A 175 mg (0.738 mmol) sample of the above 3-oxo-2-(3-phenoxyphenyl)propanenitrile was reduced using sodium cyanoborohydride (51 mg, 0.81 mmol) in ethanol (1.25 mL) and acetic acid (90 μL) using the procedure described in Example 17 to give 158 mg (89% yield) of 3-hydroxy-2-(3-phenoxyphenyl)propanenitrile as a pale yellow viscous oil.

Provenance & Evidence