Methanesulfonyl chloride → HCID 86761002, compound

HRID 1437649Notes

Reaction equation

HRID 1437649 reaction equation
Cl.[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:31])[F:30])[CH:26]=[C:25]([C:33]([F:36])([F:35])[F:34])[CH:24]=2)[CH2:19][CH2:18][NH:17][CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH3:37][S:38](Cl)(=[O:40])=[O:39]>>[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:30])([F:31])[F:32])[CH:26]=[C:25]([C:33]([F:36])([F:34])[F:35])[CH:24]=2)[CH2:19][CH2:18][N:17]([S:38]([CH3:37])(=[O:40])=[O:39])[CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 86760996HCID 86760996, compound

Product 1

HCID 86761002HCID 86761002, compound

Procedure

The compound (31.8 mg) obtained in Example 25 and methylsulfonyl chloride (9.3 μl) were reacted and treated in the same manner as in the method described in Example 30 to obtain the title compound.

Workup

  1. additiontreated in the same manner as in the method

Sources & evidence

ORD record
ord-cc8c64d876374d5892bbe29762441c49
Source dataset
uspto-grants-2009_11
Patent number
US07622487B2

Reaction notes

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