Propionic Acid → HCID 69057026, compound

HRID 1437654Notes

Reaction equation

HRID 1437654 reaction equation
Cl.[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:31])[F:30])[CH:26]=[C:25]([F:33])[CH:24]=2)[CH2:19][CH2:18][NH:17][CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[C:34](O)(=[O:37])[CH2:35][CH3:36]>>[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:30])[F:31])[CH:26]=[C:25]([F:33])[CH:24]=2)[CH2:19][CH2:18][N:17]([C:34](=[O:37])[CH2:35][CH3:36])[CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 1032Propionic AcidHCID 69059221HCID 69059221, compound

Product 1

HCID 69057026HCID 69057026, compound

Procedure

The compound (28.8 mg) obtained in Example 26 and propionic acid (9.0 μl) were reacted and treated in the same manner as in the method described in Example 33 to obtain the title compound.

Workup

  1. additiontreated in the same manner as in the method

Sources & evidence

ORD record
ord-0a43d80cdc5a4c5cb8008c8c88b93e9a
Source dataset
uspto-grants-2009_11
Patent number
US07622487B2

Reaction notes

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