2-Pyridineacetic acid, hydrochloride (1:1) → HCID 69058680, compound

HRID 1437663Notes

Reaction equation

HRID 1437663 reaction equation
Cl.[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:31])[F:30])[CH:26]=[C:25]([F:33])[CH:24]=2)[CH2:19][CH2:18][NH:17][CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.Cl.[N:35]1[CH:40]=[CH:39][CH:38]=[CH:37][C:36]=1[CH2:41][C:42](O)=[O:43]>>[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:30])[F:31])[CH:26]=[C:25]([F:33])[CH:24]=2)[CH2:19][CH2:18][N:17]([C:42](=[O:43])[CH2:41][C:36]2[CH:37]=[CH:38][CH:39]=[CH:40][N:35]=2)[CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 853172-Pyridineacetic acid, hydrochloride (1:1)HCID 69059221HCID 69059221, compound

Product 1

HCID 69058680HCID 69058680, compound

Procedure

The compound (28.8 mg) obtained in Example 26 and 2-pyridineacetic acid hydrochloride (20.8 mg) were reacted and treated in the same manner as in the method described in Example 32 to obtain the title compound.

Workup

  1. additiontreated in the same manner as in the method

Sources & evidence

ORD record
ord-38dc97300a7948f58165fce20dc090cb
Source dataset
uspto-grants-2009_11
Patent number
US07622487B2

Reaction notes

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