1,3-Benzodioxole-5-carboxylic acid → HCID 69057064, compound

HRID 1437665Notes

Reaction equation

HRID 1437665 reaction equation
Cl.[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:31])[F:30])[CH:26]=[C:25]([F:33])[CH:24]=2)[CH2:19][CH2:18][NH:17][CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[C:34](O)(=[O:44])[C:35]1[CH:43]=[CH:42][C:41]2[O:40][CH2:39][O:38][C:37]=2[CH:36]=1>>[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:30])[F:31])[CH:26]=[C:25]([F:33])[CH:24]=2)[CH2:19][CH2:18][N:17]([C:34]([C:35]2[CH:43]=[CH:42][C:41]3[O:40][CH2:39][O:38][C:37]=3[CH:36]=2)=[O:44])[CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 71961,3-Benzodioxole-5-carboxylic acidHCID 69059221HCID 69059221, compound

Product 1

HCID 69057064HCID 69057064, compound

Procedure

The compound (28.8 mg) obtained in Example 26 and piperonylic acid (19.9 mg) were reacted and treated in the same manner as in the method described in Example 33 to obtain the title compound.

Workup

  1. additiontreated in the same manner as in the method

Sources & evidence

ORD record
ord-41bdcb8ed9184b39a28e63eb3c92f4e4
Source dataset
uspto-grants-2009_11
Patent number
US07622487B2

Reaction notes

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