Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 2-Isopropoxyphenol | HCID 20949 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Isopropoxyphenyl acetate | HCID 57073664 | — |
Reaction Steps
To a solution of 2-isopropoxyphenol (1.53 g, 10 mmol) in CH2Cl2 at 0° C., was added pyridine (1.76 mL, 22 mmol) followed by acetyl chloride (0.79 mL, 1.1 eq). The mixture was stirred at 0° C. for 1.0 h, diluted with diethyl ether, washed with 5% citric acid and brine. The organic extract was dried over Na2SO4, evaporated to give 2-isopropoxyphenyl acetate as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07622585B2 |
|---|
| Source dataset | uspto-grants-2009_11 |
|---|
| ORD ID | ord-ebc96bdde0394ea9a2a433d9d864786e |
|---|
| Source note | uspto-grants-2009_11 |
|---|
