HCID 67439156, compound → HCID 131727789, compound

HRID 1438131Notes

Reaction equation

HRID 1438131 reaction equation
NC1C=CC(S(C(C)C)(=O)=O)=C([C@H]2[C@H](C(OC)=O)CCN2C(OC(C)(C)C)=O)C=1.[ClH:30].[CH:31]([S:34]([C:37]1[CH:42]=[CH:41][C:40]([C:43]([O:45][CH3:46])=[O:44])=[CH:39][C:38]=1[C@H:47]1[C@@H:51]([C:52]([O:54][CH3:55])=[O:53])[CH2:50][CH2:49][NH:48]1)(=[O:36])=[O:35])([CH3:33])[CH3:32]>>[ClH:30].[CH:31]([S:34]([C:37]1[CH:42]=[CH:41][C:40]([C:43]([O:45][CH3:46])=[O:44])=[CH:39][C:38]=1[C@@H:47]1[C@H:51]([C:52]([O:54][CH3:55])=[O:53])[CH2:50][CH2:49][NH:48]1)(=[O:36])=[O:35])([CH3:33])[CH3:32]

Participants

3

Reactant 2

HCID 67439156HCID 67439156, compoundHCID 68438876HCID 68438876, compound

Product 1

HCID 131727789HCID 131727789, compound

Procedure

61D was prepared from 61B using a procedure similar to that used in the preparation of 61C. 1H NMR (400 MHz, Methanol-d4) δ ppm 1.29 (d, J=6.60 Hz, 3H) 1.33 (d, J=6.85 Hz, 3H) 2.46-2.64 (m, 1H) 2.61-2.83 (m, 1H) 3.39-3.47 (m, 3H) 3.45-3.65 (m, 2H) 3.68-3.79 (m, 1H) 3.77-3.84 (m, 3H) 3.83-3.95 (m, 1H) 5.86 (d, J=8.31 Hz, 1H) 7.58 (d, J=8.80 Hz, 1H) 7.89 (s, 1H) 7.96 (d, J=8.80 Hz, 1H).

Sources & evidence

ORD record
ord-a7d6e3d89bfa42edb5b39d1e845e83e7
Source dataset
uspto-grants-2009_11
Patent number
US07622585B2

Reaction notes

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