HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Ethoxy-5-ethyl-2-fluorophenyl)-2-hydroxyacetonitrile → 2-(5-Ethyl-2-fluoro-3-methoxyphenyl)-2-hydroxyacetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Ethoxy-5-ethyl-2-fluorophenyl)-2-hydroxyacetonitrile | HCID 57942800 | — |
| Reactant | 5-Ethyl-2-fluoro-3-methoxybenzaldehyde | HCID 59838048 | — |
| Product | 2-(5-Ethyl-2-fluoro-3-methoxyphenyl)-2-hydroxyacetonitrile | HCID 59838005 | — |
Reaction Steps
119B was prepared from 119A using a procedure similar to that used in the preparation of 118E. 1H NMR (400 MHz, CDCl3) δ ppm 1.23 (t, J=7.47 Hz, 3H) 2.64 (q, J=7.62 Hz, 2H) 3.89 (s, 3H) 5.76 (s, 1H) 6.86 (dd, J=7.91, 2.20 Hz, 1H) 6.98 (dd, J=5.93, 1.98 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07622585B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-99bd70eb62ba42deaace1ff199e1c0b3 |
| Source note | uspto-grants-2009_11 |