HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(3-ethoxy-5-ethyl-2-fluorophenyl)-2-hydroxyacetate → Methyl 2-(5-ethyl-2-fluoro-3-methoxyphenyl)-2-hydroxyacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(3-ethoxy-5-ethyl-2-fluorophenyl)-2-hydroxyacetate | HCID 57942688 | — |
| Reactant | 2-(5-Ethyl-2-fluoro-3-methoxyphenyl)-2-hydroxyacetonitrile | HCID 59838005 | — |
| Product | Methyl 2-(5-ethyl-2-fluoro-3-methoxyphenyl)-2-hydroxyacetate | HCID 59838057 | — |
Reaction Steps
119C was prepared from 119B using a procedure similar to that used in the preparation of 118F. 1H NMR (400 MHz, CDCl3) δ ppm 1.21 (t, J=7.69 Hz, 3H) 2.59 (q, J=7.47 Hz, 2H) 3.76 (s, 3H) 3.87 (s, 3H) 5.38 (s, 1H) 6.65-6.85 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07622585B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-d116da0978604a0c8d50f494b347d03a |
| Source note | uspto-grants-2009_11 |