HCID 67444123, compound → HCID 57448187, compound

Participants

Reaction Steps

137F (130 mg, 0.29 mmol) was dissolved in THF (8 mL). To this solution was added 10% Pd/C (cat.), and the mixture was hydrogenated at 50 psi for 16 h. The reaction was filtered and concentrated to provide 2-(1-aminoisoquinolin-6-yloxy)-2-(3,4-dimethoxyphenyl)acetic acid (113 mg, 10%). LC-MS: 355.19 (M+H)+.

Provenance & Evidence