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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1438180Generated: October 27, 2026

Methyl 2-(3,4-dimethoxyphenyl)-2-hydroxyacetate → Methyl 2-(2-fluoro-4,5-dimethoxyphenyl)-2-hydroxyacetate

https://huagongshe.com/reaction/1438180

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3,4-dimethoxyphenyl)-2-hydroxyacetateHCID 597469—
Reactant2-Fluoro-4,5-dimethoxybenzaldehydeHCID 603595—
ProductMethyl 2-(2-fluoro-4,5-dimethoxyphenyl)-2-hydroxyacetateHCID 5744818844%

Reaction Steps

139A (1.05 g, 44%) was prepared in 2 steps from 2-fluoro-4,5-dimethoxybenzaldehyde following procedures analogous to those used in the preparation of 137B. LC-MS: 267.11 (M+Na)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07622585B2
Source datasetuspto-grants-2009_11
ORD IDord-ec601ef46e0247fd910c644d5cc5fa22
Source noteuspto-grants-2009_11