Ethanol → Tert-butyl 4-hydroxypiperidine-1-carboxylate

HRID 143861Notes

Reaction equation

HRID 143861 reaction equation
[BH4-:15].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[CH3:17][CH2:18][OH:19].[Na+:16]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([OH:14])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 702EthanolHCID 923Sodium ionHCID 28123BorohydrideHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylate

Sources & evidence

ORD record
ord-aa88b7eab5a1466e9bf47d7842bf3bd4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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